CONTENT OF THE COURSES

ATATURK’S PRINCIPLES AND THE HISTORY OF TURKISH RENOVATION  I

The characteristics of the Turkish Republic and Atatürk's reforms in their cultural, ideological and historical context. Study of the intellectual foundations of Modern Turkey

TURKISH LANGUAGE I

Explanation of communication; explanation of language and its relationship with thinking process, culture, society and literature; written and oral communication; illustration of main characteristics of the Turkish language, types of narration and its defects.

GENERAL CHEMISTRY

The structure and classification of substance, the structure of atom,  periodic table, gas laws, liqiud phase,  the phase diagrams, chemical bonds,  the basic laws of the chemistry, the mole, chemical equations and its calculations, solutions and solubility, acid and base reactions, oxidation-reduction reactions, thermochemistry, radioactivity,

GENERAL PHYSICS I

Physics and measurement. Vectors. One dimensional motion. Two dimensional motion. Newton's motion laws. Circular motion. Work and Energy. Potential Energy and Conservation of energy. Linear momentum; Impulse; Collisions. Rotation of a Rigid Object About a Fixed Axis.  Angular Momentum. Static Equilibrium and Elasticity. Oscillatory Motion. Universal Gravitation.

TECHNICAL ENGLISH I

Basic technical english vocabulary in the field of bioengineering, determination  and calculation of bioengineering, cell culture, biomaterials, molecular biology and basic terminology of genetics. Calculus I Trigonometry; Functions; The limit of a function; Calculating limits using the limit laws; The derivative of a function; Maximum minimum values; The mean value theorem ; Linear approximations; determinate forms and L’Hospital’s rule; Optimization problems; Curve sketching

INTRODUCTION TO INFORMATION SYSTEMS

Informatic technologies, fundamentals concepts of hardware and softwares, general processing systems, word processing programs, electronic tabling programs, data presentation, use of internet.

INTRODUCTION TO BIOENGINEERING

A detailed explanation of bioengineering, history and future of bioengineering, study areas of bioengineering, bioprocess technology, ethics in bioengineering and recent technology in the field of bioengineering

ATATURK’S PRINCIPLES AND THE HISTORY OF TURKISH RENOVATION  II

Analysis of the main political, social, economic and cultural currents in the Republican era. Nation state and nationalism as a major force in Turkey.

TURKISH LANGUAGE  II

Properties of "narration" and its types; writing and communication modes; exemplified by selected masterpieces of Turkish and world literature.

GENERAL BIOLOGY

Basic principles of biological system. Topics include cell biology, atomic basis of life, little creatures, biodiversity, cell structure and function, energy production, ecology, cell metabolism, plant and animal tissue culture, cell division, photosynthesis, the origion and history of life, genetics, energy metabolims, organ structure, physiology of plant and animal.                                           

ORGANIC CHEMISTRY

Introduction to Organic Chemistry, Electronic Structure of Atom, Chemical Bonds, Hybridization, Formulas of Organic Compounds, Isomery, Lewis Constructions and Formal Charge, Inductive and Mezomer Effect, Electrofilic and Nucleofilic Compounds, Theory of Acid-Base, Reactions in Organic Chemistry, Alkanes, Alkenes, Alkynes, Organic Halogen Compounds, Alcohols and Ethers, Aldehydes and Ketones, Carboxylic Acids, Amines, Lipids and Detergents, Amino Acids and Proteins, Aromatic Compounds, Organic Sulphur Compounds, Carbohydrates.

BASIC COMPUTER PROGRAMMING

Introduction to programming, algorithms and flowcharts, introduction to MATLAB, Solution of linear systems of equations using MATLAB. Input/output and formatting commands; Programming; Mathematical functions; Vector, matrix and array commands; Plotting commands; Numerical methods; Symbolic math toolbox; MATLAB solutions to the bioengineering problem set.

GENERAL PHYSICS  II

Electric fields. Gauss law. Electric potential. Capacitance and dielectrics. Current and resistance. Direct current circuits. Magnetic fields. Sources of the magnetic field. Faraday's law. Inductance. Alternating current circuits. Electromagnetic waves.

TECHNICAL ENGLISH II

Technical English II for bioengineers, Heat Transfer, Mass Transfer, Thermodynamics, Separation Techniques for bioengineers, terminology of Biotransport, Bioreactors, Bioprocess and Biocencors.

CALCULUS II

Anti-derivatives, Indefinite Integrals;  The substitution rule; Integration by parts; Trigonometric integrals; Integration of rational functions by partial fractions; The definite integrals; Area of a surface of revolution; Applications to engineering; The integral test and estimates of sums ; Representations of functions as power series; Taylor and Maclaurin series; Solutions of systems of linear equations; Matrices; Gauss-Jordan elimination: solving systems of equations; Determinants, Inverse of a square matrix, Cramer’s rule

DIFFERENTIAL EQUATIONS

Classification of differential equations and their solutions, Initial value problems and boundary value problems, formation of differential equations. Separable differential equations, exact differential equations, homogeneous differential equations, differential equations with linear coefficients, linear differential equations, Bernoulli differential equations, Riccati differential equations, Equations reducible to exact differential equations. Basic theory of higher order differential equations, Reduction of order, Homogeneous differential equations with constant coefficients, Nonhomogeneous differential equations with constant coefficients and their solution methods: method of variation of parameters, method of undetermined coefficients, Cauchy-Euler differential equations

FLUIDS MECHANICS

The concept of fluid, the physical properties of fluids, pressure distribution in fluids. basic laws of fluid mechanics, Reynolds theorem, the general momentum and energy balances, pumps and compressors. Measurement of fluid flow, compressible fluid flow, flow in open channels, Flow around immersed bodies, flow through packed beds.

PHYSICAL CHEMISTRY

Gas laws, the properties of liquids, solids and gases, their mixtures and their properties, the basic principles and applications of absorption, adsorption, distillation and extraction,  chemical kinetics, colloid chemistry, ęntroduction to thermodynamics, Enzyme kinetics,

BIOSTATISTICS

Introduction to basic statistical terminology and concepts, describing data, itroduction to widely used statistical methods for in the field of environment, biology and genetics,

CELL BIOLOGY

What is a cell made of? What are cells? Origion and type of cell, methods in cell biology, microscopy, type of microscopes, chemistry of cells, cell wall, cell matrix, protein transportation, apoptosis and cancer.

BIOCHEMISTRY

Biomolecules and cell structure, amino acids, peptide bonds and properties, structure and classification of proteins, protein purification, classification and recognition reactions of carbohydrates, lipids and membrane structure, Classification of enzymes,enzyme kinetics and biotechnological applications of enzymes, fermentation technologies.

MATERIALS AND ENERGY BALANCES

Fundamental concepts, material and energy conservation laws, the continuous and discrete processes. Back and forth, and loop-powered systems, material and energy balances. The calculations concerned with combustion and flue gas analysis. Calculation of mass and energy balances in industrial applications

MICROBIOLOGY

Comprehensive overview of microbiology with emphasis of  physiological, biogeochemical, ecological, evolutionary aspects of microorganisms. Introduction to biology of microorganisms including structure, function, metabolism, growth, genetics, diversity. Introduction to microbiological laboratory techniques and application including microscopy, enrichment and isolation, cultivation and preservation. Covers a wide range of topics including antibiotics, biofilms, fungi, bacteriophage, quorum sensing and role of microorganisms in environmental porcess.

GENERAL PHYSIOLOGY

General Physiology is to introduce the fundamental mechanisms of human, animal and plants physiology. Basic cellular physiology, body functions and molecular mechanism will be discussed. Furthermore, emphasis will be placed on nervous, muscular, cardiovascular, respiratory, renal, digestive, and endocrine physiology. Organismal physiology of plants, metabolic processes, water relations, mineral nutrition, morphogenesis. Effects of light, natural rhythms, temperature, and other environmental factors on plant growth.

THERMODYNAMICS

Energy conversion and general energy balance, pure substances properties, first law of thermodynamic and application closed system,  the analysis of mass and energy balance at the control volume, second law of thermodynamic, entropy, solving second law of thermodynamics, vapour power cycle, Refrigeration cycle, chemical reaction, chemical equilibrium, enthalpy and entropy correlation

MASS TRANSFER

This course explains the determination methods of the amount of materials transferred per unit time and area through the mathematical expressions of the variation of concentration profiles that are considered as the fundamental concept of interphase mass transport processes encountered in separation processes and chemical reactions.

MOLECULAR BIOLOGY

Basic terminology for molecular biology, basic molecular biology techniques and applications including  DNA manipulation, PCR, sequencing, plasmid, vectors, cloning, subcloning, library construction and screening, RNA isolation and characterization analysis of cDNA synthesis (RT-PCR),purification of proteins and characterization of proteins. Furthermore, it includes molecular biological techniques in biotechnology and other industries i.e. pharmaceutical will be presented and molecular methods and applications will be highlighted.

GENETICS

Human, microbial and viral genomes, gene expression, matabolic regulation of procaryotes. Basic principles of diognostic tests, viroids and prions, types of viruses, biotechnological applications of viruses.

PRINCIPLES AND TECHNIQUES OF BASIC LABORATORY

Introduction to basic laboratory techniques, general terminology, magnetic field, electric, voltage and ampere, solvents, quantitative and qualitative analysis of important biological molecules, introduction to microscopy, cell type, plant and animal tissues, biodiversity.

INTRODUCTION TO BIOPROCESS ENGINEERING

Overview of kinetics of microbial growth, substrate utilization. Sterilization of media, batch and continous processes, mass transfer in bioreactors and basic introduction to scale-up concepts.

BIOMATERIALS

Definition of biomaterials, application of biomaterials, introduction implant materials and classification. Topics covered include: reasons for implant failure, a brief introduction to relevant tissue types: anatomy, biochemistry and physiology. Concepts of biocompatibility, host response, material degradation, testing and selection, standards.

BIOENGINEERING LAB I

Sterilization and how to prepare the media, characterization of pure culture, staining of microorganisms, determination of biomass concentration, microbial growth kinetics, production of alpha amilaze enzyme.

BIOSENSORS

Overview of common biochemical interactions used quantify biological molecules, recent electronic technologies used to detect them. A detailed explanation of biosensors, miniaturization and applications related to agricaulture, medicine and environment.

HEAT TRANSFER

One dimensional heat transfer. Steady-state conduction and convection; General energy equation, Transient conduction and convection. heat transfer with heat source.  Thermal and hydrodynamic boundary layer concepts; Forced convection, Free convection; Heat exchangers; heat transfer with boiling and phase change, Radiation heat transfer; Finned surfaces.

PRINCIPLES OF BIOTRANSPORTS

Introduction of basic phenomena with emphases on applying key transport concepts, quantitative description of momentum transport and mass transport in living systems. A brief description of Fundamentals węth conservation laws to develop mathematical description of physiological and engineering systems.

BIOREACTORS

Introduction to bioreactors and basic terminology of bioreactors, properities of biocatalizers, design of bioreactors, parameters for select best bioreactors, calculation methods and different types of bioreactors.

BIOPROCESS CONTROL

Control of biological process by using mathematicals modelling, mechanism of feed back.

INTRODUCTION TO BIOINFORMATICS

Introduction to biological databases, latest techniques for  bioinformatics, analysis and interpretation of  various type of biological data including, nucleotide and amino acid sequences, protein structures and protein domains, development of new algorithms and statistics. Overview of how to manage to work large data sets and how to make a phylogenetic tree by using 16S rRNA results. Examples of biological data used in the field of bioinformatics.

BIOENGINEERING LAB II 

Sterilization and preparing the media, isolation of pure culture, staining thecniques of microorganisms, biomass control, microbiological growth kinetics, DNA isolation, PCR applications, mass transfer in bioreactors, heat transfer, detection of vitamin C.

IMMUNOLOGY

A detailed explanation of the immune system, devolopment of immune system, organs of immune system, cells of the immune system, molecules of immune system, innate immunity and immune response to bacteria and viruses

CELL CULTURE

A detailed introduction to fundamental methods used to grow cells in culture. Topics in this course include aseptic technique, preparation and use of various culture media, cell counting and dilution, origin and uses of various cell lines, contamination and quality control. Furthermore, overview of survey of metabolism, cell structure and function, growth factors and signal transduction.

SEPERATION AND PURIFICATION PROCESS

Evaporation, moistening and drying, Absorption, Distillation, Solid liquid extraction (leaching), Liquid-liquid extraction, membrane separation processes, filtration, adsorption, mixing, crystallization, such as the basic principles of separation processes, applications and describes the foundation of industrial designs.

GENETIC ENGINEERING

Introduction to genetic engineering and methods, clonning, recomninant DNA technology, DNA manupulation. Overview of recent technologies in the field of genetic engineering. 

PROCESS DESIGN

Principles and methods of design, introduction of process design,  process modelling and simulation, preparation of heat and mass balance, process flow diagrams, sizing the process equipments, preparation piping and instrument diagram, utilities and common facility system.

BIOENGINEERING PROJECTS

Students will be expected to combine theoretical and practical ability for preperation a bioengineering project and a presentation to class.

ECONOMICS FOR ENGINEERS

Different concepts of economics, basics of bonds and stocks and their valuation,  principles of economic equivalence; time value of money; analysis of single and multiple investments; comparison of alternatives; capital recovery and tax implications; certainty; uncertainty; risk analysis; public sector analysis and break-even concepts.

BIOTECHNOLOGY

This course introduce both applications and principles of recombinant DNA technology to microorganisms, plants and animals. It also cove a detailed explanation of biotechnology includes history and applications of recent DNA/RNA thecnology, molecular biology, recent technologies to clean the environment and improve human health.

ETHICS IN BIOENGINEERING

The field of Bioengineering focuses on the application and development of new technologies in medicine and biology. These new technologies has powerful effects on the living systems. On the one hand they can provide great opportunities and benefit to society, but on the other hand it can be used in dangerous ways. So, it is extreemly important that bioengineers understand the basic principles of ethics. This course will provide both societal and personal ethical principles.

BIOENGINEERING PROJECTS

Students will be expected to combine theoretical and practical ability for preperation a bioengineering project and a presentation to class.


TECHNICAL ELECTIVE


WATER TECHNOLOGY

Properties and molecular structure of water; Alkalinity and hardness in water accounts; Dissolved oxygen and biochemical oxygen demand; Physical treatment processes, sedimentation; Coagulation, flotation and filtration; Chemical treatment processes, separation by precipitation; Treatment with ion exchange method, cation exchangers; Industrial water; Dissolved oxygen removal, Cooling water, drinking water

FUEL AND COMBUSTION TECHNOLOGY

Formation and classification of fossil fuels. Physical and chemical properties of fuels. Clean coal technologies. Combustion mechanism. Combustion systems and classification. Improving of the fossil fuels and the evaluation of wastes.

ENERGY TECHNOLOGIES

Energy and resources. Force, work, power, the first law of thermodynamics. World and Turkey's energy balance. Fossil fuels. New and renewable energy sources. Conservation and transport of energy.

CORROSION

Introduction to corrosion ; The electrochemical mechanism of corrosion; The corrosion types; Thermodynamic approaches to corrosion; Potential-pH diagrams; The corrosion engineering;;The protection from corrosion

INDUSTRIAL ELECTROCHEMISTRY

The basic concepts of electrochemistry and electrolysis, Faraday Laws, Current Density and Current Yield, Nernst Equation, Electrode Kinetics, Corrosion, Classification of Electrodes, Technical Electrolytic Methods and General Principles,  Metal Coating, Obtaining Copper and Zinc Electrolytically, Electrolysis of Alkali Chlorides, Chlor-Alkali Processes, Electrometallurgy.

INTRODUCTION TO POLYMER TECHNOLOGY

Provide to  the fundamental knowledge to students about  definition of polymer,polymers industries and raw materials, structure of polymers, chemical bonds structure and relationships of polymers, viscosity and molecule weight of polymers, synthesis of polymers, additives used to enhance the properties of polymers, industrial polymerization processes, basic features of polymers, polymer recycle and industries.

ENVIRONMENTAL TECHNOLOGY

The fundamentals of ecology, the fundamentals of ecology, ecological effects of global warming and climate change, ecological effects of ozone depletion, environmental impacts of energy production and renewable energy esources, environmental impacts of population growth, air pollution, water pollution, soil pollution, solutions to environmental problems.

BIOTECHNOLOGY OF ARCHAEA

 An Introduction to Archaea. Phylogeny of Archaea, cell types, function and molecular biology of Archaea, important Archaeal genus in biotechnical applications.  A detailed explanation of Crenarchaeota and Euryarchaeota. Extremophilic Archaea, molecular basis of heat resistance, screening strategies for detection of novel enzymes from Archaea.

INTRODUCTION TO PHARMACOLOGY

Overview of applications of biotechnology and pharmaceutical biotechnology,introduction to basic pharmacology and terminology, applied pharmoclogy with emphasis of basic principles to each organ system , therapuctics and future direction of therapeutics, advance pharmacological principles such as cancer therapeutics. 

BIOREMEDIATION: PRINCIPLES AND APPLICATION

Knowing and understanding the microbial process is so important in environmental management. Microorganisms and their mechanisms play an essential role in different type of environment includes soils, streams , lakes and ocean. Topics cover definition and history of bioremidiation, principles of bioremediation, types of bioremidiation with special emphasis on the ground water bioremediation, recent technologies in the field of bioremediation, different bioremediation strategies (in situ, solid phase, slurry phase and vapor phase) advantages and disadvantages of bioremediation and natural attenuation.

MOLECULAR MICROBIAL ECOLOGY: APPLICATIONS AND TECHNIQUES

Topics cover definition of microbial ecology, recent molecular applications in the field of microbial ecology such as PCR, library construction, RTpcr and mRNA studies, FISH  and SIP techniques. Focus on the microbial communities, dominate soil, artric, marine and freshwater environments and interaction between the macro and micro organisms.  To provide basic knowledge on the use of molecular methods for identicfication, characterization and ecophysiological properities of microorganism.

EPIGENETICS

Definition of epigenetics, overview of epigenetics regülation types.

INDUSTRIAL ENZYMES

Application araes of important industrial enzymes, examples of different types of industrial enzymes.

COMPUTER APPLICATIONS IN BIOTECHNOLOGY

Many data have been obtained in the field of molecular biology and biotechnology and the numbers are increasing too rapidly. There is a big gap evaluation and modelling of these data. This can be accomplish by present computer technology. Computer applications in the field of biology, and several examples of these application will be prensented during the course.

OPTIMIZATION

Terms and concepts of optimization, Formulation of the optimization problems. Optimization of one and two variable functions.  Multivariable optimization techniques, Direct search methods, classical optimization methods, optimization of heat exchanger and chemical reactors, Lagrange multiplier, nonlinear programming, Dynamic programming.

STANDARDIZATION AND QUALITY

The relations between the quality and standard. Certification and accreditation. Standards producers, consumers and contributions to the national economy. Objectives and activities of the Turkish Standards Institute. Standard preparation. Metrology and calibration. Documents from the Turkish Standards Institute. Quality and total quality management. TS-ISO 9000 quality management and quality assurance standards. TS-ISO 14000 environmental management standards. TS-EN 45000 accreditation standards.

FACTORY ORGANIZATION

General information about the industrial establishments, Plant placement and organization. Work study and planning. Quality control. cost estimations Risk assessment of investments, Product quality assurance,  work safety –health and work accidents.

BIOFUELS

Biomass raw materials. Types of biofuels. Review of the fossil-based fuels. Technologies and processes for the production of biofuels from biomass. Biofuel production methods. Biodiesel as a biofuel, and other fuels. Biofuel production in the world and in Turkey.

SENSOR TECHNOLOGY

Basic Concepts of Sensors, Introduction to Sensors and Brief History, Introduce the Electrochemical Cells and Components, Types of Electrodes, Reference Electrodes, Solid Metal Electrodes, Ion Selective Electrodes, Electrochemical Analysis Methods and Electrochemical Sensors, Modified Electrode Preparation Methods, Application Areas of Modified Electrodes, Optical and Thermal Sensors, Mass-Sensitive Sensors, Biosensors and Application Areas, Enzymes and Enzyme Immobilization Methods, Enzyme, DNA, and Optical Biosensors, Some Chemical and Biosensors Used in Application.

INDUSTRIAL WASTEWATER TREATMENT

Waste water and its specifications and analysis; Municipal wastes waters, industrial waste waters and their analysis; Physical refining methods; chemical refining methods; Chemical oxidation and disinfection; Biological refining methods;

SOLID WASTE RECYCLING

Waste treatment, waste types; Classification of wastes, evaluation of solid wastes; Operations on municipal solid wastes; The criteria’s of European Union about solid wastes;  Plastic wastes and recycling

MICROBIAL PHYSIOLOGY

Introduction to microbial physiology, synthesis of macromolecules, microbial growth, effect of environment, energy and metobolism, cell wall and cell membrane, ecology and adaptation to extreme environment.

PRINCIPLES AND APPLICATIONS OF ANAEROBIC BIOTECHNOLOGY

Basic fundamental concepts in anaerobic treatment and process, microbiology of anaerobic treatment, biochemical interactions, factors effecting biochemical reactions, relationship between anaerobic system and bioreactors, kinetics and models, process monitoring , anaerobic biotechnology, anaerobic sludge treatment.

ENVIRONMENTAL MICROBIOLOGY

Overview of environmental microbiology, function and roles of microorganisms in nature, a detailed explanation and importance of water and soil microbiology, diversity of microorginisms. Biogeochemical cycling, biotic and abiotic factors, interaction and behaviour of microorganisms.important microorganisms in industrial processes,essential of anabolism, classification of microorganisms,  applications of microorganisms to solve environmental problems. 

INTRODUCTION TO SYSTEM BIOLOGY

Basic principles of system biology, modelling of biochemical reactions, biological networks, analysis biological systems and simulation.

INTRODUCTION TO PERMACULTURE

Definition and basic principles of permaculture, introduction to recent permaculture desęgns advantages of permaculture, recycles and reuse of waste, recyling strategies for better life, organic growing,  design and strategies, use of energy efficent, understanding sustainability, micro-climate strategies.

PLANT CELL CULTURE

Applications areas of plant cell culture, importance of plant cell culture in Industry and new methods in the plant cell culture will be discussed.  

MICROBIAL AND VIRAL GENETICS

Study on the prokaryotic and viral genome organization, different mechanism for aranging gene regulation.

STERILIZATION TECHNIQUES

Overview of sterilization techniques and preparation before the sterilization.

NON-TECHNICAL ELECTIVE


GENERAL MANAGEMENT

Main elements and concept definition of management, purpose of management, classification based on the different factors, stage of bussiness organization, bussiness size dimensions. Detailed study of business function, management, production, marketing, finance and other functions. 

HISTORY OF SCIENCE

Scientific activities in antiquity, scientific relationship amongs Egypt, Mesopotamia, Greece, Greeks and Romans, examples of current sociological study, developmental stages of modern science, the industrial revolution and the new physical theories,

PROJECT AND TIME MANAGEMENT

Brief summary of research project, important parameters to start the research project, importance of literature review, narrowing the topics, determine the  hypothesis, reasearch goals for short and long term, analysis of results. Overview of importance of time management, goal setting (SMART goals, visualisation), prioritising your time, how to plan the activities wisely, organising your workspace, setting a ritual, managing project and inspired action, tools that really work. It also offers format achieving the balance between personal and professional life. 

PRESENTATION SKILLS

Introduction of Poweroint technologies, font and heads arragements, how to prepare oral presentation, how to prepare tables andn figures for nice presentation, selecting the word, strategies for managing the questions after the presentation, team Works.